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Research
Enhanced Fluorescence
Using a photonic crystal structure with an optical resonance that matches the wavelength of a laser used to excite fluorescent molecules, we can excite adsorbed fluorescent-tagged biomolecules and cells to emit more light than they would on an ordinary surface. At the same time, a photonic crystal surface can also have a resonance at the wavelength of light given off by fluorescent molecules, so that emitted photons can be directed toward a microscope objective. The enhanced excitation and extraction phenomena can be used to detect fluorescent-tagged proteins and DNA with greater sensitivity than currently-used methods – enabling advances in gene expression analysis for humans and crops, and the ability to detect disease biomarkers at low concentrations.
Follow the links below to learn more about the mechanisms for enhancing fluorescence using photonic crystal structures, and some of the applications for this approach being developed in the Nano Sensors Group.
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 Research Areas
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