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Research
High Throughput Drug Screening
One of the important applications for biosensors is to help chemists and molecular biologists sort through huge “libraries” of chemical compounds that potentially have important pharmaceutical properties. For example, pharmaceutical researchers work to understand the protein-protein interactions that take place within our cells that lead to a particular disease, and wish to find chemical molecules that effectively stops a critical interaction from occurring, thus preventing the disease. Because the interaction of small chemical molecules with proteins is currently not completely predictable, researchers often test hundreds of thousands of different chemicals. It is important to perform these tests quickly, so the ability to perform them in a “high throughput” fashion will reduce the amount of time it takes to test an entire library.
We are collaborating with research groups in the University of Illinois Chemistry Department and the Beckman Institute to use photonic crystal biosensors for high throughput screening for applications in Parkinson’s disease and cancer.
Follow the links below to learn more about collaborative project in which we are using biosensor technology as a screening tool for cell-based and biomolecule-based drug discovery.
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 Research Areas
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